Bakopa monnieri, yomwe imadziwikanso kuti brahmi mu Sanskrit ndi tonic ya ubongo mu Chingerezi, ndi zitsamba zomwe zimagwiritsidwa ntchito kwambiri ku Ayurvedic. Kafukufuku watsopano wasayansi akuti zitsamba za Indian Ayurvedic Bacopa monnieri zasonyezedwa kuti zimathandiza kupewa matenda a Alzheimer's (AD). Ndemangayi, yofalitsidwa m'magazini yotchedwa Science Drug Target Insights, inachitidwa ndi gulu la ofufuza a ku Malaysia ochokera ku yunivesite ya Taylor ku United States ndipo adawona zotsatira za thanzi la bacosides, gawo la bioactive la zomera.
Potchula maphunziro awiri omwe adachitika mu 2011, ofufuzawo adanena kuti ma bacosides amatha kuteteza ubongo ku kuwonongeka kwa okosijeni komanso kuchepa kwa chidziwitso chokhudzana ndi ukalamba kudzera munjira zingapo. Monga non-polar glycoside, ma bacosides amatha kuwoloka chotchinga chamagazi-muubongo kudzera munjira yosavuta ya lipid-mediated passive diffusion. Kutengera ndi kafukufuku wam'mbuyomu, ofufuzawo adati ma bacosides amathanso kupititsa patsogolo chidziwitso chifukwa cha zomwe amawononga mwaulere.
Ubwino wina waumoyo wabacosideszikuphatikizapo kuteteza ma neurons ku Aβ-induced toxicity, peptide yomwe imagwira ntchito yofunika kwambiri pa matenda a AD chifukwa imatha kusonkhana mu insoluble amyloid fibrils. Ndemangayi ikuwonetsa ntchito zogwira mtima za Bacopa monnieri muzogwiritsira ntchito chidziwitso ndi neuroprotective, ndipo ma phytoconstituents angagwiritsidwe ntchito popanga mankhwala atsopano.Zomera zambiri zachikhalidwe zimakhala ndi zosakaniza zovuta za mankhwala omwe ali ndi zochitika zosiyanasiyana zamankhwala ndi zachilengedwe, makamaka Bacopa monnieri, zomwe zimagwiritsidwa ntchito. monga mankhwala azikhalidwe komanso pakupanga zinthu zoletsa kukalamba.
● Ubwino Sikisi WaBacopa Monnieri
1.Imakulitsa Kukumbukira ndi Kuzindikira
Bacopa ili ndi zabwino zambiri zokopa, koma mwina imadziwika bwino chifukwa chakutha kukumbukira komanso kuzindikira. The choyambirira limagwirira ndiBakopakumawonjezera kukumbukira ndi kuzindikira ndi kudzera mukulankhulana bwino kwa synaptic. Mwachindunji, zitsamba zimalimbikitsa kukula ndi kufalikira kwa dendrites, zomwe zimapangitsa kuti mitsempha iwonetsere.
Zindikirani: Ma dendrites ndi ma cell a mitsempha ngati nthambi omwe amalandira zizindikiro zomwe zikubwera, kotero kulimbikitsa "mawaya" awa a mauthenga a mitsempha pamapeto pake kumawonjezera ntchito ya chidziwitso.
Kafukufuku wapeza kuti Bacoside-A imayambitsa ma cell a mitsempha, zomwe zimapangitsa kuti ma synapses agwirizane ndi zomwe zikubwera. Bacopa yasonyezedwanso kuti imapangitsa kukumbukira ndi kuzindikira mwa kulimbikitsa zochitika za hippocampal powonjezera ntchito ya protein kinase m'thupi, yomwe imasintha njira zosiyanasiyana zama cell.
Popeza hippocampus ndi yofunika kwambiri pazochitika zonse zamaganizo, ofufuza amakhulupirira kuti iyi ndi imodzi mwa njira zazikulu zomwe Bacopa amawonjezera mphamvu za ubongo.
Kafukufuku wina wasonyeza kuti tsiku ndi tsiku supplementation ndiBakopa monnieri(pa Mlingo wa 300-640 mg patsiku) ukhoza kusintha:
Memory ntchito
Spatial memory
Chikumbukiro chosazindikira
Chidwi
Mtengo wophunzirira
Kuphatikiza kukumbukira
Kuchedwa kukumbukira ntchito
Kukumbukira mawu
Kukumbukira kowonekera
2.Kuchepetsa Kupsinjika Maganizo ndi Nkhawa
Kaya ndi zachuma, chikhalidwe, thupi, maganizo, kapena maganizo, nkhawa ndi nkhani yaikulu m'miyoyo ya anthu ambiri. Masiku ano, kuposa ndi kale lonse, anthu akuyesetsa kuti athawe mwa njira iliyonse, kuphatikizapo mankhwala osokoneza bongo ndi mowa. Komabe, zinthu monga mankhwala osokoneza bongo ndi mowa zimatha kusokoneza maganizo ndi thupi la munthu.
Mungakonde kudziwa zimenezoBakopaali ndi mbiri yakale yogwiritsidwa ntchito ngati dongosolo lamanjenje lothandizira kuthetsa nkhawa, nkhawa, ndi kupsinjika maganizo.Izi ndi chifukwa cha Bacopa's adaptogenic properties, zomwe zimapangitsa kuti thupi lathu lizitha kupirira, kuyanjana, ndi kuchira ku nkhawa (maganizo, thupi). , ndi maganizo). Bacopa imakhala ndi machitidwe osinthika awa mwa zina chifukwa cha kuwongolera kwake kwa ma neurotransmitters, koma zitsamba zakalezi zimakhudzanso milingo ya cortisol.
Monga mukudziwira, cortisol ndiye mahomoni ofunikira m'thupi. Kupsinjika kwanthawi yayitali komanso kuchuluka kwa cortisol kumatha kuwononga ubongo wanu.M'malo mwake, akatswiri asayansi apeza kuti kupsinjika kwanthawi yayitali kungayambitse kusintha kwanthawi yayitali muubongo ndi magwiridwe antchito, zomwe zimapangitsa kuti mapuloteni ena awononge ma neuroni.
Kupsinjika kwakanthawi kumabweretsanso kuwonongeka kwa okosijeni kwa ma neuron, komwe kumatha kukhala ndi zotsatira zoyipa zosiyanasiyana, kuphatikiza:
Kulephera kukumbukira
Kufa kwa ma cell a neuron
Kusokoneza zisankho
Atrophy ya ubongo wambiri.
Bacopa monnieri ali ndi mphamvu zochepetsera kupsinjika, zoteteza ku ubongo. Kafukufuku wa anthu adalemba zotsatira za adaptogenic za Bacopa monnieri, kuphatikizapo kuchepetsa cortisol. Kutsika kwa cortisol kumabweretsa kuchepa kwa kupsinjika, komwe sikungowonjezera kusinthasintha, komanso kukulitsa chidwi ndi zokolola. Kuphatikiza apo, chifukwa Bacopa monnieri imayang'anira dopamine ndi serotonin, imatha kuchepetsa kusintha komwe kumayambitsa kupsinjika kwa dopamine ndi serotonin mu hippocampus ndi prefrontal cortex, kutsindikanso za adaptogenic za zitsamba izi.
Bakopa monnieriimawonjezeranso kupanga tryptophan hydroxylase (TPH2), puloteni yomwe imakhala yofunikira pazochitika zosiyanasiyana zamanjenje zapakati, kuphatikizapo serotonin synthesis. Chofunika kwambiri, bacoside-A, imodzi mwazinthu zomwe zimagwira ntchito mu Bacopa monnieri, yawonetsedwa kuti imathandizira ntchito ya GABA. GABA ndi neurotransmitter yodekha, yoletsa. Bacopa monnieri imatha kuwongolera zochitika za GABA ndikuchepetsa zochita za glutamate, zomwe zingathandize kuchepetsa nkhawa mwa kuchepetsa kuyambitsa kwa ma neuron omwe angakhale opitilira muyeso. -zabwino" vibe.
Nthawi yotumiza: Oct-08-2024
