• Kodi Ndi Chiyani?Mtengo PQQ ?
PQQ, dzina lonse ndi pyrroloquinoline quinone. Monga coenzyme Q10, PQQ ndi coenzyme ya reductase. M'munda wa zakudya zowonjezera zakudya, nthawi zambiri zimawoneka ngati mlingo umodzi (mu mawonekedwe a mchere wa disodium) kapena mu mawonekedwe a mankhwala ophatikizidwa ndi Q10.
Kupanga kwachilengedwe kwa PQQ ndikotsika kwambiri. Imapezeka m'nthaka ndi tizilombo tating'onoting'ono, zomera ndi nyama, monga tiyi, natto, kiwifruit, ndi PQQ imapezekanso m'matenda a anthu.
Mtengo PQQali ndi ntchito zambiri zokhudza thupi. Itha kulimbikitsa mitochondria yatsopano m'maselo (mitochondria amatchedwa "zomera zopangira mphamvu zama cell"), kotero kuti liwiro la kaphatikizidwe ka mphamvu yama cell liwonjezeke kwambiri. Kuphatikiza apo, PQQ yatsimikiziridwa m'maphunziro a nyama ndi anthu kuti azitha kugona, kuchepetsa cholesterol, kuchepetsa kupsinjika kwa okosijeni, kutalikitsa moyo, kulimbikitsa kugwira ntchito kwaubongo ndikuchepetsa kutupa.
Mu 2017, gulu lofufuza lomwe linapangidwa ndi Pulofesa Hiroyuki Sasakura ndi ena ochokera ku yunivesite ya Nagoya ku Japan adafalitsa zotsatira zawo zafukufuku m'magazini "JOURNAL OF CELL SCIENCE". Coenzyme pyrroloquinoline quinone (PQQ) imatha kutalikitsa moyo wa nematodes.
• Kodi Ubwino Wathanzi Ndi Chiyani?Mtengo PQQ ?
PQQ Imalimbikitsa Mitochondria
Pakufufuza kwa nyama, ofufuza ku Yunivesite ya California adapeza kuti PQQ imatha kulimbikitsa kupanga mitochondria yathanzi. Mu kafukufukuyu, mutatha kutenga PQQ kwa milungu 8, kuchuluka kwa mitochondria m'thupi kuwirikiza kawiri. Mu kafukufuku wina wa nyama, zotsatira zake zidawonetsa kuti chitetezo chamthupi chidachepetsedwa kwambiri ndipo kuchuluka kwa mitochondria kudachepetsedwa popanda kutenga PQQ. PQQ itawonjezedwanso, zizindikirozi zidabwezeretsedwanso.
Kuchepetsa kutupa ndikuteteza nyamakaziAntioxidant & chitetezo cha mitsempha
Nthawi zambiri okalamba amavutika ndi nyamakazi, yomwenso ndi chinthu chofunikira kwambiri chomwe chimatsogolera ku chilema. Kafukufuku wasonyeza kuti chiwerengero cha anthu omwe amafa ndi matenda a nyamakazi ndi 40% kuposa chiwerengero cha anthu ambiri. Chifukwa chake, gulu la asayansi lakhala likuyesetsa kufunafuna njira zopewera ndi kuthetsa matenda a nyamakazi. Kafukufuku yemwe adasindikizidwa posachedwa m'magazini ya Inflammation akuwonetsa kutiMtengo PQQakhoza kukhala mpulumutsi wa nyamakazi yemwe ofufuza akhala akuyang'ana.
Pakuyesa kwachipatala kwa anthu, asayansi adayerekeza kutupa kwa chondrocyte mu chubu choyesera, adabaya PQQ m'gulu limodzi la maselo, ndipo sanabaye gulu lina. Zotsatira zake zidawonetsa kuti kuchuluka kwa ma collagen ochepetsa ma enzymes (matrix metalloproteinases) m'gulu la chondrocyte omwe sanabayidwe ndi PQQ adakwera kwambiri.
Kudzera mu maphunziro a mu vitro ndi mu vivo, asayansi apeza kuti PQQ imatha kuletsa kutulutsidwa kwa zinthu zotupa ndi ma cell a fibrotic synovial m'malo olumikizirana, kwinaku akuletsa kuyambitsa kwa zinthu zolembera za nyukiliya zomwe zimayambitsa kutupa. Nthawi yomweyo, asayansi apezanso kuti PQQ imatha kuchepetsa ma enzymes ena (monga matrix metalloproteinases), omwe amaphwanya ma collagen amtundu wa 2 m'malo olumikizirana mafupa ndikuwononga mafupa.
Antioxidant & chitetezo cha mitsempha
Kafukufuku wapeza kutiMtengo PQQali ndi neuroprotective zotsatira pa makoswe midbrain neuronal kuwonongeka ndi Parkinson matenda chifukwa rotenone.
Kusagwira ntchito kwa Mitochondrial ndi kupsinjika kwa okosijeni kwawonetsedwa kuti ndizomwe zimayambitsa matenda a Parkinson (PD). Kafukufuku wasonyeza kuti PQQ ili ndi mphamvu ya antioxidant ndipo imatha kuteteza ku cerebral ischemia pokana kupsinjika kwa okosijeni. Kuyankha kupsinjika kwa okosijeni kumawonedwa kuti ndi imodzi mwanjira zofunika kwambiri zomwe zimatsogolera ku cell apoptosis. PQQ imatha kuteteza maselo a SH-SY5Y ku rotenone (neurotoxic agent) -induced cytotoxicity. Asayansi adagwiritsa ntchito PQQ pretreatment kupewa rotenone-induced cell apoptosis, kubwezeretsa kuthekera kwa nembanemba ya mitochondrial, ndikuletsa kupanga kwamtundu wa okosijeni wa intracellular (ROS).
Kawirikawiri, kufufuza mozama pa ntchito yaMtengo PQQpa thanzi lathupi kungathandize anthu kupewa kukalamba.
• Zatsopano ZatsopanoMtengo PQQUfa /Makapisozi/Mapiritsi/Gummies
Nthawi yotumiza: Oct-26-2024
