M'zaka zaposachedwapa, chinthu amatchedwaNicotinamide Riboside(NR) yakopa chidwi chambiri mumagulu asayansi ndi zaumoyo. NR ndi kalambulabwalo wa vitamini B3 ndipo imatengedwa kuti ili ndi mphamvu zotsutsana ndi ukalamba ndi chisamaliro chaumoyo, ndipo ikukhala malo otentha kwambiri pa kafukufuku ndi chitukuko.
NRzapezeka kuti zikuwonjezera kuchuluka kwa ma intracellular a NAD +, coenzyme yofunikira yomwe imakhudzidwa pakuwongolera kagayidwe kachakudya ndi kupanga mphamvu. Pamene zaka zikuchulukirachulukira, milingo ya NAD+ m'thupi la munthu imachepa pang'onopang'ono, ndipo kuwonjezera kwa NR kumatha kuthandizira kukhalabe ndi milingo yapamwamba ya NAD +, yomwe ikuyembekezeka kuchedwetsa ukalamba ndikuwongolera magwiridwe antchito a cell.
Kuphatikiza pa mphamvu zake zoletsa kukalamba,NRzapezeka kuti zili ndi zotsatira zabwino paumoyo wamtima, thanzi la metabolic, ndi neuroprotection. Kafukufuku akuwonetsa kuti NR imatha kupititsa patsogolo kayendedwe ka mitsempha ya magazi, kuchepetsa kuchuluka kwa mafuta m'thupi, kuchepetsa mayankho otupa, komanso kukhala ndi phindu popewa matenda amtima. Kuphatikiza apo, NR imakhulupiriranso kuti imathandizira kuwongolera kuchuluka kwa shuga m'magazi, kukonza chidwi cha insulin, ndikuthandizira kupewa matenda a shuga ndi kunenepa kwambiri. Pankhani ya neuroprotection, NR yapezeka kuti imathandizira kupanga mphamvu zama cell aubongo ndipo ikuyembekezeka kuchitapo kanthu popewa matenda a neurodegenerative.
Pamene kafukufuku wa NR akupitirizabe kuzama, makampani ochuluka a zaumoyo akuyamba kuwonjezera NR monga chinthu chofunika kwambiri pazaumoyo kuti akwaniritse zosowa za anthu zotsutsana ndi ukalamba ndi chisamaliro chaumoyo. Nthawi yomweyo, mayesero ena azachipatala akuchitikanso kuti atsimikizire kugwira ntchito ndi chitetezo cha NR m'magawo osiyanasiyana azaumoyo.
NgakhaleNRali ndi kuthekera kwakukulu, kafukufuku wochulukirapo akufunika kuti atsimikizire zotsatira zake zanthawi yayitali komanso chitetezo. Kuonjezera apo, anthu amafunikanso kusankha mankhwala a NR mosamala kuti atsimikizire kuti magwero awo ndi khalidwe lawo ndi lodalirika. Pamene kafukufuku ndi chitukuko cha NR chikupitirirabe kukula, ndikukhulupirira kuti zidzabweretsa zatsopano komanso chiyembekezo ku thanzi laumunthu.
Nthawi yotumiza: Aug-29-2024
