Kodi Ndi ChiyaniGlabridin?
Glabridin ndi flavonoid yotengedwa ku mizu ya licorice (Glycyrrhiza glabra) ndipo imakhala ndi zochitika zosiyanasiyana zamoyo komanso thanzi labwino. Glabridin imadziwika ndi kuyera kwamphamvu, antioxidant ndi anti-inflammatory properties ndipo imagwiritsidwa ntchito kwambiri posamalira khungu ndi zodzoladzola.
Glycyrrhiza glabra L. ndi zitsamba zosatha zomwe zimamera kum'mwera kwa Ulaya, Asia, ndi dera la Mediterranean. Amabzalidwa kwambiri ku Russia, Spain, Iran, ndi India. Chomera cha G. glabra ndi chautali wa mamita 1-1.5, ndi masamba ang'onoang'ono obiriwira, achikasu, abuluu, ndi maluwa a violet, ndi rhizome yokoma.
Glabridin ndi imodzi mwa flavonoids yayikulu mu Glycyrrhiza glabra. Imawonetsa mphamvu yotsutsa-free radical oxidation effect mu cytochrome P450/NADPH oxidation system, ndipo imatha kuletsa kwambiri ma free radicals opangidwa panthawi ya metabolism m'thupi kuti ateteze ma biomacromolecules a oxidation (otsika osalimba lipoprotein LDL, DNA) ndi makoma a cell kuti asawonongeke ndi ma free radical oxidation. Izi zitha kuteteza ndi kuchiza kusintha kwa pathological komwe kumakhudzana ndi ma free radical oxidation, monga atherosulinosis ndi kukalamba kwa maselo. Kuphatikiza apo, glabridin imakhala ndi zotsatira zina zochepetsera lipids ndi kuthamanga kwa magazi. Kafukufuku wa ku Italy watsimikiziranso kuti Glabridin ali ndi chilakolako chochepetsera chilakolako, chomwe chingachepetse mafuta popanda kuchepetsa kulemera. Pambuyo poyesedwa mobwerezabwereza, zotsatira zake zazikulu ndi izi: 1. Whitening, inhibiting melanin; 2. Anti-yotupa zotsatira; 3. Antioxidant zotsatira; 4. Antibacterial.
Zakuthupi ndi Zamankhwala zaGlabridin
1. Kapangidwe ka Mankhwala
Dzina la mankhwala: Glabridin
Chilinganizo cha Chemical: C20H20O4
Kulemera kwa Maselo: 324.37 g/mol
Makhalidwe Apangidwe: Glabridin ndi gulu la flavonoid lomwe lili ndi mawonekedwe a msana wa flavonoid. Amakhala ndi mphete ziwiri zonunkhiritsa (A ndi B) zolumikizidwa ndi mlatho wa carbon atatu womwe umapanga mphete yotsekeka ya pirani.
2. Katundu Wakuthupi
Maonekedwe: Glabridin nthawi zambiri imawoneka ngati ufa woyera kapena wotumbululuka wachikasu.
Kusungunuka:
Madzi: Sasungunuka m’madzi.
Organic Solvents: Kusungunuka mu zosungunulira za organic monga ethanol, methanol, ndi propylene glycol.
Malo Osungunuka: Pafupifupi 156-158 ° C (313-316 ° F).
Kununkhira: Glabridin nthawi zambiri alibe fungo lodziwika.
3. Chemical Properties
Kukhazikika: Glabridin imakhala yosasunthika m'mikhalidwe yabwinobwino koma imatha kutsika ikakumana ndi kuwala, kutentha, kapena acidic. Ndibwino kuti muzisunga pamalo ozizira, ouma, kutali ndi dzuwa.
pH Sensitivity: Glabridin imakhudzidwa ndi kusintha kwa pH ndipo imatha kutsika m'malo okhala acidic kwambiri kapena oyambira.
Reactivity: Monga flavonoid, glabridin imatha kukumana ndi zochitika zamagulu zomwe zimagwirizanitsidwa ndi mankhwala a phenolic, monga oxidation ndi conjugation.
Kodi Ubwino Wake Ndi ChiyaniGlabridin?
1. Khungu Kuyera ndi Kuwala
- Kuletsa kwa Tyrosinase: Glabridin imadziwika bwino chifukwa choyeretsa khungu. Imalepheretsa ntchito ya tyrosinase, puloteni yofunika kwambiri pakupanga melanin, motero imachepetsa mapangidwe a mdima komanso hyperpigmentation.
- Ngakhale Khungu la Khungu: Pochepetsa kaphatikizidwe ka melanin, glabridin imathandizira kuti khungu likhale lowala komanso lowala.
2. Antioxidant Properties
- Free Radical Scavenging: Glabridin ili ndi mphamvu ya antioxidant, yomwe imathandizira kuletsa ma radicals aulere. Izi zimachepetsa kupsinjika kwa okosijeni ndikuletsa kuwonongeka kwa ma cell.
- Anti-Kukalamba: Ntchito ya antioxidant ya glabridin imathandiza kuchepetsa zizindikiro za ukalamba, monga mizere yabwino, makwinya, ndi madontho a zaka, poteteza khungu ku kuwonongeka kwa okosijeni.
3. Anti-Kutupa Zotsatira
- Kuchepetsa Kutupa: Glabridin amawonetsa anti-inflammatory properties, zomwe zimathandiza kuchepetsa kutupa kwa khungu, kufiira, ndi kutupa.
- Kutsitsimula: Imatha kutsitsimula khungu lokwiya komanso imathandiza pazifukwa monga ziphuphu zakumaso, eczema, ndi rosacea.
4. Antimicrobial Activity
- Kuletsa tizilombo toyambitsa matenda: Glabridin wasonyeza antimicrobial katundu motsutsana mabakiteriya osiyanasiyana ndi bowa. Izi zimapangitsa kuti zikhale zothandiza popewa komanso kuchiza matenda a pakhungu.
- Chithandizo cha Ziphuphu: Ma antimicrobial ndi anti-inflammatory properties amachititsa kuti glabridin ikhale yothandiza pochiza ziphuphu pochepetsa kukula kwa bakiteriya ndi kutupa.
5. Chitetezo cha UV
- Photoprotection: Glabridin ikhoza kupereka chitetezo china ku radiation ya UV. Zimathandizira kuchepetsa kuwonongeka kwa khungu komwe kumachitika chifukwa cha UV, monga kupsa ndi dzuwa ndi kujambula zithunzi.
- Synergistic Effect: Ikagwiritsidwa ntchito limodzi ndi othandizira ena oteteza dzuwa, glabridin imatha kupititsa patsogolo chithunzithunzi chonse.
6. Kuchiritsa Mabala
- Imalimbikitsa Machiritso: Glabridin ikhoza kulimbikitsa machiritso a bala mwa kuchepetsa kutupa ndi kupsinjika kwa okosijeni, komanso kulimbikitsa kusinthika kwa maselo a khungu.
- Kuchepetsa Zipsera: Zitha kuthandizanso kuchepetsa mawonekedwe a zipsera polimbikitsa kusinthika kwapakhungu.
7. Kusamalira Tsitsi
- Umoyo Wam'mutu: Glabridin ndi anti-inflammatory and antimicrobial properties angapindule thanzi la scalp, kuchepetsa dandruff ndi scalp.
- Kukula kwa Tsitsi: Mwa kukonza thanzi la m'mutu, glabridin imatha kulimbikitsanso kukula kwa tsitsi.
Kodi Ma Applications Ndi ChiyaniGlabridin?
Zodzoladzola ndi Skincare
1.Skin Whitening Products
- Whitening Creams and Serums: Glabridin ndi chinthu chofunikira kwambiri pakhungu zambiri zoyera komanso zowunikira chifukwa cha kuthekera kwake kuletsa ntchito ya tyrosinase ndikuchepetsa kupanga melanin.
- Chithandizo cha Spot: Amagwiritsidwa ntchito m'mapangidwe omwe cholinga chake ndi kuchepetsa mawanga akuda, hyperpigmentation, ndi khungu losagwirizana.
2.Zoletsa Kukalamba
- Anti-Aging Creams and Lotions: The antioxidant katundu wa glabridin amathandiza kuchepetsa zizindikiro za ukalamba, monga mizere yabwino, makwinya, ndi mawanga a zaka.
- Mafuta a Maso: Nthawi zambiri amaphatikizidwa ndi zopaka m'maso kuti achepetse mdima komanso kudzikuza.
3. Anti-Inflammatory and Soothing Products
- Ma Gels Otsitsimula ndi Ma Cream: Glabridin imakhala ndi anti-inflammatory properties imapangitsa kuti ikhale yoyenera kwa mankhwala omwe amapangidwa kuti azitsitsimutsa khungu lopweteka kapena lotupa.
- Chithandizo cha Ziphuphu: Amagwiritsidwa ntchito pochiza ziphuphu kuti achepetse kutupa ndi kukula kwa bakiteriya.
4. Sun Protection Products
- Zodzitetezera ku dzuwa: Glabridin ikhoza kuphatikizidwa ndi zoteteza dzuwa kuti zitetezedwe ku kuwonongeka kwa khungu lopangidwa ndi UV.
- After-Sun Care: Amagwiritsidwa ntchito popanga zinthu zapadzuwa kuti atonthoze ndi kukonza khungu lopsa ndi dzuwa.
Mankhwala
1. Mankhwala apamutu
- Anti-Inflammatory Creams: Amagwiritsidwa ntchito ngati mankhwala apakhungu pochiza matenda otupa pakhungu monga chikanga, psoriasis, dermatitis.
- Mafuta Ochiritsa Pabala: Amaphatikizidwa m'mapangidwe omwe cholinga chake ndi kulimbikitsa machiritso a zilonda komanso kuchepetsa kupangika kwa zipsera.
2. Zowonjezera Mkamwa
- Antioxidant Supplements: Glabridin's antioxidant katundu imapangitsa kuti ikhale yofunika kwambiri muzinthu zowonjezera pakamwa zomwe zimafuna kuchepetsa kupsinjika kwa okosijeni ndikulimbikitsa thanzi labwino.
- Zolimbitsa Thupi: Zimagwiritsidwa ntchito muzowonjezera zomwe zimapangidwira kuti chitetezo cha mthupi chitetezeke chifukwa cha anti-yotupa komanso antimicrobial properties.
Kusamalira Tsitsi
1.Kuchiza M'mutu
- Anti-Dandruff Shampoos: Glabridin ndi antimicrobial ndi anti-inflammatory properties zimapangitsa kuti zikhale zogwira mtima pochiza dandruff ndi scalp.
- Maselo a M'mutu: Amagwiritsidwa ntchito m'maselo a scalp kuti apititse patsogolo malo abwino a scalp komanso kulimbikitsa kukula kwa tsitsi.
2.Hair Conditioners
- Zodzoladzola ndi Masks a Tsitsi: Zimaphatikizidwa muzinthu zosamalira tsitsi kuti zipereke chitetezo cha antioxidant ndikusintha thanzi la tsitsi.
Chakudya ndi Zakumwa
Zakudya Zogwira Ntchito
- Zakumwa Zaumoyo: Glabridin akhoza kuwonjezeredwa ku zakumwa zathanzi ndi zakumwa zogwira ntchito kuti apereke antioxidant ndi anti-inflammatory properties.
- Malo Odyera Zakudya Zakudya: Amagwiritsidwa ntchito m'malo odyera zakudya komanso zokhwasula-khwasula pofuna kulimbikitsa thanzi labwino komanso thanzi.
Kafukufuku ndi Chitukuko
Kafukufuku wa Biomedical
- Kafukufuku wa Khansa: Glabridin amaphunziridwa chifukwa cha mphamvu zake zotsutsana ndi khansa, kuphatikizapo kuthekera kwake kulepheretsa kukula kwa maselo a khansa ndi kuyambitsa apoptosis.
- Kafukufuku Wamatenda Osatha: Amafufuzidwa chifukwa cha zopindulitsa zake pakuwongolera matenda osatha monga matenda a shuga ndi matenda amtima chifukwa cha anti-yotupa komanso antioxidant.
Mafunso Ofananira nawo Mungakhale Ndi Chidwi:
Zimatenga nthawi yayitali bwanji kuti licorice extractglabridinkupenitsa khungu?
Nthawi yomwe imatengera licorice Tingafinye munali glabridin kupepukitsa khungu zingasiyane malinga ndi zinthu zingapo, kuphatikizapo ndende ya glabridin mu mankhwala, pafupipafupi ntchito, munthu khungu mtundu, ndi kuopsa kwa hyperpigmentation. Nawa malangizo ndi malingaliro ena:
1. Nthawi Yofananira
- Zotsatira Zoyambirira: Ogwiritsa ntchito ena angayambe kuwona kusintha koyambirira kwa kamvekedwe ka khungu komanso kuchepa kwa hyperpigmentation mkati mwa masabata a 2 mpaka 4 ogwiritsidwa ntchito mosasinthasintha.
- Zotsatira Zofunika: Zowoneka bwino komanso zowunikira kwambiri pakhungu zimachitika pakatha masabata 8 mpaka 12 akugwiritsa ntchito pafupipafupi.
2. Zinthu Zomwe Zimakhudza Kuchita Bwino
Kukhazikika kwa Glabridin
- Kukhazikika Kwapamwamba: Zogulitsa zomwe zimakhala ndi glabridin wambiri (mwachitsanzo, 0.5% mpaka 1%) zimatha kutulutsa zotsatira zachangu komanso zodziwika bwino.
- Kutsika Kwambiri: Zogulitsa zomwe zimakhala zocheperako zitha kutenga nthawi yayitali kuti ziwonetsedwe.
Kuchuluka kwa Ntchito
- Kugwiritsa Ntchito Tsiku ndi Tsiku: Kugwiritsa ntchito mankhwalawa kamodzi kapena kawiri tsiku lililonse, monga momwe akulimbikitsira, kumatha kupititsa patsogolo mphamvu ndikufulumizitsa zotsatira.
- Kugwiritsa Ntchito Mosagwirizana: Kugwiritsa ntchito molakwika kumatha kuchedwetsa zowoneka ndikuchepetsa mphamvu zonse.
Mtundu wa Khungu ndi Mkhalidwe
- Khungu lamtundu: Anthu omwe ali ndi khungu lopepuka amatha kuona zotsatira mwachangu poyerekeza ndi omwe ali ndi khungu lakuda.
- Kuopsa kwa Hyperpigmentation: Kuchepa kwa pigmentation kumatha kuyankha mwachangu chithandizo, pomwe milandu yowopsa imatha kutenga nthawi yayitali kuti iwonetse kusintha.
3. Njira Yothandizira Khungu
- Chitetezo cha Dzuwa: Kugwiritsa ntchito mafuta oteteza ku dzuwa tsiku lililonse ndikofunikira mukamagwiritsa ntchito zowunikira pakhungu kuti mupewe kuchulukirachulukira komanso kuteteza khungu kuti lisawonongeke ndi UV.
- Moisturization: Kusunga khungu lonyowa bwino kumatha kukulitsa kuyamwa komanso kuchita bwino kwa zinthu zomwe zili ndi glabridin.
- Kutulutsa: Kutulutsa nthawi zonse kungathandize kuchotsa maselo akufa a khungu ndikulimbikitsa kulowa kwa zinthu zomwe zimagwira ntchito, zomwe zingathe kufulumizitsa zotsatira.
4. Maphunziro a Zachipatala ndi Umboni
- Maphunziro a Zachipatala: Kafukufuku wina wachipatala wasonyeza kuti glabridin ikhoza kuchepetsa kwambiri hyperpigmentation ndikusintha khungu mkati mwa masabata 8 mpaka 12 ogwiritsidwa ntchito mosasinthasintha.
- Maumboni Ogwiritsa Ntchito: Ogwiritsa ntchito ambiri anena kuti awona kusintha kowoneka bwino pakhungu lawo komanso kuchepa kwa mawanga amdima mkati mwa milungu ingapo mpaka miyezi ingapo yogwiritsa ntchito pafupipafupi.
Zotsatira zake ndi zotaniglabridin?
Glabridin ali ndi ntchito zosiyanasiyana zachilengedwe komanso thanzi labwino, koma nthawi zina, kugwiritsa ntchito mankhwala okhala ndi glabridin kungayambitse mavuto ena. Zotsatirazi ndizovuta komanso zodzitetezera za glabridin:
1. Kukwiya Pakhungu ndi Matupi Abwinons
Khungu Kukwiya
- Zizindikiro: Zitha kukhala zofiira, kutupa, kuyabwa, kuluma, kapena kuyaka.
- Zoyambitsa: Kukhudzika kwa khungu kwa glabridin kapena zosakaniza zina zomwe zimapangidwira zimatha kuyambitsa kuyabwa kwapakhungu.
Zomwe Zimayambitsa
- Zizindikiro: Zikhoza kukhala zotupa, erythema, kutupa, kapena kuyabwa kwambiri.
- Zomwe zimayambitsa: Kusagwirizana ndi glabridin kapena zosakaniza zina zomwe zimapangidwira, zomwe zingayambitse kusamvana.
2. Photosensitivity
- Kuchulukitsa Kumva Kuwala kwa Dzuwa: glabridin imatha kukulitsa chidwi cha khungu ku kuwala kwa dzuwa, zomwe zimatsogolera ku kutentha kwa dzuwa kapena photosensitivity dermatitis.
- Katetezedwe: Mukamagwiritsa ntchito mankhwala okhala ndi glabridin, tikulimbikitsidwa kugwiritsa ntchito zoteteza ku dzuwa komanso kupewa kutenthedwa ndi dzuwa kwa nthawi yayitali.
3. Zotsatira za Mahomoni
- Zomwe Zingatheke M'mahomoni: Ngakhale kuti glabridin imapangidwira kuti ikhale yogwiritsidwa ntchito pamutu, zigawo zina za licorice (monga glycyrrhizic acid) zimadziwika kuti zimakhala ndi zotsatira zofanana ndi steroid zomwe zingakhudze kuchuluka kwa mahomoni.
- Kuganizira: Mukamagwiritsa ntchito mankhwala okhala ndi glabridin mochuluka kwa nthawi yayitali, muyenera kusamala kuti muwone ngati pali zizindikiro za kusalinganika kwa mahomoni.
4. Kuyanjana ndi Zosakaniza Zina Zakhungu
- Zomwe Zingatheke: Glabridin ikhoza kuyanjana ndi zinthu zina zogwira ntchito (monga vitamini C, retinol, etc.), zomwe zimakhudza mphamvu yake kapena kuonjezera chiopsezo cha zotsatirapo.
- Malangizo: Mukamagwiritsa ntchito mankhwala okhala ndi glabridin, ndi bwino kupewa kugwiritsa ntchito zosakaniza zina zamphamvu kapena kukaonana ndi dermatologist musanagwiritse ntchito.
5. Zotsatira Zadongosolo
- Mayamwidwe Ochepa:glabridinamagwiritsidwa ntchito makamaka pa ntchito zakunja ndipo amakhala ndi mayamwidwe ochepa mwadongosolo, kotero kuti zotsatira zake zimakhala zochepa kwambiri.
- Chenjezo: Ngati mukukumana ndi vuto lililonse kapena vuto lililonse, muyenera kusiya kugwiritsa ntchito nthawi yomweyo ndipo funsani dokotala.
6. Mimba ndi Kuyamwitsa
- Zodetsa Zachitetezo: Pakali pano pali data yochepa pachitetezo cha glabridin mwa amayi oyembekezera komanso oyamwitsa.
- Malangizo: Amayi oyembekezera ndi oyamwitsa ayenera kufunsa dokotala wawo asanagwiritse ntchito mankhwala okhala ndi glabridin.
Nthawi yotumiza: Sep-21-2024
