Kodi Ndi ChiyaniGinsenosides?
Ginsenosides ndizofunikira kwambiri zomwe zimagwira ntchito mu ginseng. Iwo ndi a triterpenoid glycoside mankhwala ndipo akhoza kugawidwa mu protopanaxadiol saponins (PPD-mtundu saponins), protopanaxatriol saponins (PPT-mtundu saponins) ndi oleanane-mtundu. Ma ginsenosides opitilira 40 asiyanitsidwa ndi mizu ya ginseng.
Ginsenosides ali ndi zotsatira zambiri zochiritsira monga antioxidant, anti-inflammatory, vasodilation, anti-allergenic, ndi anti-diabetic. Ma ginsenosides ena amawonetsa mphamvu zawo zolimbana ndi khansa pochepetsa kuwonongeka kwa DNA, kuchepetsa kutengeka kwa minyewa, kukulitsa kuwunika kwa chitetezo chamthupi ndi ma cell apoptosis. Kuphatikiza apo, ma ginsenosides amatha kupititsa patsogolo mphamvu yamankhwala achikhalidwe chamankhwala komanso kupewa kuwonongeka kwa minofu yabwinobwino.
Zomwe zili mu Ginsenosides Onse M'magawo Osiyanasiyana a Ginseng
| Gawo | Zonse za Ginsenosides |
| Mizu yozungulira | 60.5% |
| Masamba | 15% |
| Ginseng masamba | 7.6% -12.6% |
| Ginseng fibrous mizu | 8.5% -11.5% |
| Ginseng khungu | 8.0% -8.8% |
| Ginseng taproot | 2% -7% |
| Ginseng achinyamata mizu | 3% |
| Mbewu | 0.7% |
Mitundu ndi Chemical Properties OfGinsenosides
Ginsenosides onse ali ndi mapangidwe ofanana, onse amakhala ndi sterane steroid nucleus yokhala ndi ma atomu 30 a carbon opangidwa mu mphete zinayi. Amagawidwa m'magulu awiri molingana ndi mitundu yosiyanasiyana ya glycoside: mtundu wa dammarane ndi mtundu wa oleanane.
Mtundu wa Dammarine uli ndi magulu awiri:
Ginsenoside mtundu-A, aglycone ndi 20 (S) -protopanaxadiol. Muli ginsenosides kwambiri, monga ginsenoside Rg3, Rb1, Rb2, Rb3, Rc, Rd, Rh2 ndi glycoside PD;
Ginsenoside mtundu-B, aglycone ndi 20 (S) -protopanaxadiol. Muli ginsenoside Re, Rg1, Rg2, Rh1 ndi glycoside PT.
Mtundu wa oleanane: oleanolic acid mtundu-C, aglycone ndi oleanolic acid.
Ma saponins onse sali a hemolytic, mtundu A ndi anti-hemolytic, pomwe mtundu B ndi mtundu C ndi hemolytic.
| Mitundu ya Ginsenoside | Kuchita bwino |
| Rh2 | Zimakhala ndi zotsatira zolepheretsa metastasis ya maselo a khansa ku ziwalo zina, kupititsa patsogolo chitetezo cha mthupi, ndikubwezeretsa mwamsanga thupi. Ili ndi mphamvu yotsutsa-metastasis pama cell a khansa, ndipo imatha kutengedwa ndi opaleshoni kuti ipititse patsogolo machiritso a chilonda ndi kuchira pambuyo pa opaleshoni. Mtheradi wa bioavailability ndi (16.1±11.3)%. |
| Rg | Imakhala ndi zotsatira zolimbikitsa dongosolo lapakati lamanjenje, kukana kutopa, kuwongolera kukumbukira ndi kuphunzira, komanso kulimbikitsa kaphatikizidwe ka DNA ndi RNA. Imakhala ndi zotsatira zolimbikitsa dongosolo lapakati lamanjenje, kukana kutopa, kuwongolera kukumbukira ndi kuphunzira, komanso kulimbikitsa kaphatikizidwe ka DNA ndi RNA. |
| Rg1 | Imatha kuthetsa kutopa msanga, kuwongolera kuphunzira ndi kukumbukira, komanso kuchedwetsa kukalamba. Lili ndi zotsatira zolimbikitsa chapakati mantha dongosolo ndi inhibiting platelet aggregation. |
| Rg2 | Ili ndi anti-shock effect, imathandizira msanga myocardial ischemia ndi hypoxia, komanso imathandizira ndikuletsa matenda amtima. |
| Rg3 | Ikhoza kuchitapo kanthu pa gawo la G2 la kubereka kwa maselo, kulepheretsa kaphatikizidwe ka mapuloteni ndi ATP mu gawo la pre-mitotic la maselo a khansa, kuchepetsa kuchulukira ndi kukula kwa maselo a khansa, ndipo zimakhala ndi zotsatira zolepheretsa kulowetsedwa kwa maselo a khansa, kukana chotupa cell metastasis, kulimbikitsa chotupa cell apoptosis, ndi kuletsa chotupa selo kukula. |
| Rg5 | Imaletsa kulowetsedwa kwa maselo a khansa, anti-chotupa cell metastasis, kulimbikitsa chotupa cell apoptosis, kuletsa kukula kwa chotupa. |
| Rb1 | Ginseng waku America (ginseng waku America) ali ndi zinthu zambiri ndipo amatha kukhudza machende a nyama komanso kukula kwa mbewa. Lili ndi ntchito yopititsa patsogolo dongosolo la choline, kuonjezera kaphatikizidwe ndi kumasulidwa kwa acetylcholine ndikuwongolera kukumbukira. |
| rb2 | Kukwezeleza kaphatikizidwe ka DNA ndi RNA, kuwongolera pakati paubongo kumakhala ndi zotsatira zolepheretsa dongosolo lapakati lamanjenje, kuchepetsa calcium, anti-oxidation, kuwononga ma radicals aulere m'thupi ndikuwongolera kuwonongeka kwa myocardial ischemia-reperfusion. |
| Rc | Ginsenoside-Rc ndi molekyulu ya steroid mu ginseng. Lili ndi ntchito yoletsa maselo a khansa. Ikhoza kuonjezera ntchito ya umuna. |
| rb3 | Ikhoza kupititsa patsogolo ntchito ya myocardial ndikuteteza chitetezo cha mthupi. Itha kugwiritsidwa ntchito pochiza kulephera kwa myocardial contractile chifukwa chazifukwa zosiyanasiyana. |
| Rh | Imakhala ndi zotsatira zoletsa dongosolo lapakati lamanjenje, hypnotic, analgesic, bata, antipyretic, ndikulimbikitsa kaphatikizidwe ka seramu mapuloteni. |
| Rh1 | Zili ndi zotsatira zolimbikitsa kuchuluka kwa maselo a chiwindi ndi kaphatikizidwe ka DNA, ndipo zingagwiritsidwe ntchito pochiza ndi kupewa matenda a chiwindi ndi matenda a cirrhosis. |
| R0 | Ili ndi anti-yotupa, detoxifying, ndi anti-thrombotic effect, imalepheretsa kuphatikizika kwa ma platelet acid, ndipo imakhala ndi zotsatira zotsutsana ndi chiwindi ndipo imayambitsa macrophages. |
| Rh3 | Zotsatira za ginsenoside Rh3 pakukula ndi kufalikira kwa maselo a khansa yamtundu wa SW480. |
Zosakaniza za anti-chotupa
| Zosakaniza | Kuchita bwino |
| Rh2 | Ginsenoside Rh2 monomer imalepheretsa kukula kwa ma cell a khansa, imatha kuyambitsa chotupa cell apoptosis, kusintha kusiyana kwachilendo kwa maselo otupa, komanso kukana metastasis ya chotupa. Akagwiritsidwa ntchito limodzi ndi mankhwala a chemotherapy, amatha kuwonjezera mphamvu ndikuchepetsa kawopsedwe. Kuphatikiza pa anti-chotupa kwenikweni, ginsenosides ali ndi zotsatira zowongolera chitetezo chamthupi, antibacterial, kuwongolera mtima ndi cerebrovascular kusakwanira kwa magazi, kuwongolera dongosolo lapakati lamanjenje, anti-kutopa, komanso kuchedwetsa kukalamba. |
| Rh1 | Ikhoza kulepheretsa kuphatikizika ndi kulowa kwa maselo a chotupa, kuteteza mapangidwe atsopano a mitsempha ya maselo a khansa, potero kulepheretsa kukula kwa chotupa, kufalikira ndi metastasis, ndipo imakhala ndi ntchito yotsutsa khansa. Itha kusintha kwambiri kuchepa kwa maselo oyera amwazi omwe amayamba chifukwa cha radiotherapy, chemotherapy ndi opaleshoni, ndikupanga rheology yamagazi kukhala yabwinobwino. Chogwiritsira ntchitochi chimakhala ndi mphamvu yoteteza komanso yotsutsa khansa, imatha kupititsa patsogolo ntchito yaumunthu ndi chitetezo cha mthupi, ndipo imakhala ndi zotsatira zazikulu kuphatikizapo opaleshoni ndi radiotherapy ndi chemotherapy. |
| Rg5 | Rg5 imatha kuyambitsa apoptosis yama cell osiyanasiyana otupa. Rg5 yotengedwa kuchokera ku ginseng yakuda yatsimikizika m'maselo am'mawere amunthu. Rg5 imathanso kuyambitsa apoptosis ndi kuwonongeka kwa DNA m'maselo osiyanasiyana a khansa ya khomo lachiberekero. Aseries of in vitro kuyesera atsimikizira kuti ginsenoside Rg5 ili ndi zoletsa pama cell a khansa ya esophageal. |
| Rh3 | Ginsenoside Rh3 imatha kuletsa kuchuluka kwa maselo a khansa ya m'matumbo amunthu SW480 ndikupangitsa apoptosis, ndipo zotsatira zake zimadalira mlingo komanso zimadalira nthawi. |
| APPD | 20 (S) - Protopanaxadiol (aPPD) ndi chinthu chogwiritsidwa ntchito ndi mphamvu ya mankhwala opangidwa ndi ginsenosides pambuyo pa desugar metabolism ndi activation ndi zomera zam'mimba, ndipo imakhala ndi zotsatira zambiri zotsutsana ndi chotupa. M'zaka zaposachedwa, gulu lofufuza la William Jia la University of British Columbia lachita kafukufuku wambiri pa anti-chotupa ntchito ya PPD mu vivo ndi mu vitro, ndipo idapeza kuti ili ndi zotsatira zapawiri zamankhwala. Kumbali imodzi, imatha kupha mwachindunji maselo otupa ndikulimbikitsa apoptosis; Komano, imatha kuteteza ma neuroni kuzinthu za cytotoxic. |
Ubwino Wake Ndi ChiyaniGinsenosides?
Ubwino wa ginsenosides, mankhwala omwe amapezeka mu ginseng, ndi osiyanasiyana ndipo akhala akufufuza kafukufuku wambiri. Ubwino wina wa ginsenosides ndi awa:
1. Ntchito Yachidziwitso: Ginsenosides adaphunziridwa chifukwa cha kuthekera kwawo kuthandizira ntchito yachidziwitso, kuphatikizapo kukumbukira, kuganizira, ndi kumveka bwino m'maganizo.
2. Mphamvu ndi Mphamvu: Ginsenosides amakhulupirira kuti ali ndi adaptogenic properties, zomwe zimathandiza kuthandizira milingo ya mphamvu, kuchepetsa kutopa, ndi kulimbikitsa mphamvu zonse.
3. Thandizo la Chitetezo cha Mthupi: Kafukufuku wina amasonyeza kuti ginsenosides ali ndi zotsatira zowononga chitetezo cha mthupi, zomwe zingathe kuthandizira chitetezo cha mthupi.
4. Kuwongolera Kupanikizika: Ginsenosides amaonedwa kuti ndi adaptogens, zomwe zikutanthauza kuti zimathandiza thupi kuti lizigwirizana ndi kupsinjika maganizo ndikulimbikitsa kukhala ndi moyo wabwino.
5. Thanzi Lamtima: Kafukufuku wina adafufuza momwe ginsenosides angathere pothandizira thanzi la mtima, kuphatikizapo zotsatira zake pa kuthamanga kwa magazi ndi kuyendayenda.
Ndikofunika kuzindikira kuti phindu lenileni la ginsenosides limasiyana malinga ndi mtundu wa ginseng ndi mapangidwe a ginsenosides omwe alipo. Monga chowonjezera chilichonse kapena zinthu zachilengedwe, ndikofunikira kukaonana ndi katswiri wazachipatala kuti mupeze upangiri wamunthu wokhudzana ndi kugwiritsa ntchito ginsenosides pazaumoyo.
Kodi Kugwiritsa Ntchito Ginsenosides Ndi Chiyani?
Ginsenosides ali ndi mitundu yambiri yogwiritsira ntchito chifukwa cha mitundu yosiyanasiyana ya mankhwala. Zina mwazogwiritsira ntchito ginsenosides ndi izi:
1. Mankhwala Achikhalidwe: Ginsenosides akhala akugwiritsidwa ntchito kwa zaka mazana ambiri muzamankhwala, makamaka ku East Asia, chifukwa cha adaptogenic ndi kulimbikitsa thanzi.
2. Zowonjezera: Ginsenosides amagwiritsidwa ntchito kwambiri monga zowonjezera zowonjezera zakudya ndi mankhwala opangira zitsamba zomwe zimapangidwira kuthandizira chidziwitso, mphamvu za mphamvu, ndi thanzi labwino.
3. Mankhwala: Kafukufuku wokhudzana ndi mankhwala omwe angakhalepo a ginsenosides apangitsa kuti azigwiritsa ntchito mankhwala opangira mankhwala, makamaka pakupanga mankhwala a zinthu monga kuchepa kwa chidziwitso, kutopa, ndi kusokonezeka maganizo.
4. Zodzoladzola: Ginsenosides amagwiritsidwanso ntchito m'makampani opanga zodzoladzola chifukwa cha ubwino wa khungu lawo, kuphatikizapo anti-kukalamba ndi antioxidant katundu.
5. Zakudya Zogwira Ntchito ndi Zakumwa: Ginsenosides amaphatikizidwa muzakudya zosiyanasiyana zogwira ntchito ndi zakumwa, monga zakumwa zopatsa mphamvu ndi zopatsa thanzi, kuti apereke ubwino wathanzi.
Kodi Mbali Yake Ndi ChiyaniGinsenosides?
Ginsenosides nthawi zambiri amawonedwa ngati otetezeka akagwiritsidwa ntchito pamlingo woyenera, koma monga gulu lililonse la bioactive, amatha kukhala ndi zotsatira zoyipa, makamaka akamwedwa mochuluka. Zotsatira zina za ginsenosides zingaphatikizepo:
1. Kusagona tulo: Mlingo wambiri wa ginsenosides ungayambitse kukondoweza, zomwe zimapangitsa kuti zikhale zovuta kugona kapena kugona.
2. Nkhani Zam'mimba: Anthu ena amavutika ndi kugaya chakudya, monga nseru, kutsekula m'mimba, kapena kukhumudwa m'mimba, akamamwa ginsenosides wambiri.
3. Kuthamanga kwa magazi: Nthawi zambiri, kumwa kwambiri ginsenosides kungayambitse kuthamanga kwa magazi.
4. Kusamvana: Ngakhale kuti si zachilendo, anthu ena akhoza kusagwirizana ndi ginsenosides, zomwe zimayambitsa zizindikiro monga zidzolo, kuyabwa, kapena kupuma movutikira.
5. Zotsatira za Hormonal: Ginsenosides akhoza kukhala ndi zotsatira zochepa za mahomoni, ndipo nthawi zina, amatha kuyanjana ndi mankhwala okhudzana ndi mahomoni kapena mikhalidwe.
Ndikofunika kuzindikira kuti zotsatira za ginsenosides zimatha kusiyana malinga ndi munthu, mtundu wa ginseng, ndi mlingo wake. Monga momwe zilili ndi zowonjezera zilizonse kapena mankhwala achilengedwe, ndi bwino kukaonana ndi akatswiri azachipatala musanagwiritse ntchito ginsenosides, makamaka kwa omwe ali ndi vuto la thanzi kapena omwe amamwa mankhwala.
Mafunso Ofananira nawo Mungakhale Ndi Chidwi:
Ndani sayenera kumwa ginseng?
Anthu ena ayenera kusamala kapena kupewa kumwa ginseng, kuphatikizapo:
1. Amayi Oyembekezera kapena Oyamwitsa: Chitetezo cha ginseng pa nthawi yoyembekezera komanso yoyamwitsa sichinafufuzidwe mozama, motero tikulimbikitsidwa kupewa kugwiritsidwa ntchito kwake panthawiyi.
2. Anthu Omwe Ali ndi Matenda a Autoimmune: Ginseng imatha kulimbikitsa chitetezo chamthupi, zomwe zitha kukulitsa mikhalidwe ya autoimmune. Ndikoyenera kuti anthu omwe ali ndi vuto la autoimmune afunsane ndi akatswiri azachipatala asanagwiritse ntchito ginseng.
3. Anthu Omwe Ali ndi Matenda Osokoneza Magazi: Ginseng ikhoza kukhala ndi zotsatira zochepetsetsa za anticoagulant, kotero anthu omwe ali ndi vuto la magazi kapena omwe amamwa mankhwala ochepetsa magazi ayenera kugwiritsa ntchito ginseng mosamala komanso motsogoleredwa ndi dokotala.
4. Anthu Amene Ali ndi Vuto Losamva Ma Hormone: Chifukwa cha kutha kwa mahomoni a ginseng, anthu omwe ali ndi vuto lokhudzidwa ndi mahomoni monga khansa ya m'mawere, uterine fibroids, kapena endometriosis ayenera kukaonana ndi dokotala asanagwiritse ntchito ginseng.
5. Amene Ali ndi Matenda Osowa tulo kapena Nkhawa: Ginseng ikhoza kukhala ndi zotsatira zolimbikitsa, choncho anthu omwe ali ndi vuto la kusowa tulo kapena nkhawa ayenera kusamala akamagwiritsa ntchito ginseng, makamaka pamene akumwa kwambiri.
Kodi ginsenosides steroids?
Ginsenosides si steroids. Ndi gulu lazinthu zachilengedwe zomwe zimapezeka mu chomera cha ginseng. Ngakhale ma ginsenosides angakhale ndi ubwino wosiyanasiyana wa thanzi, amapangidwa mwadongosolo komanso mogwira ntchito mosiyana ndi ma steroid. Steroids ndi gulu la mahomoni ndi lipids omwe amagwira ntchito yofunika kwambiri mu kagayidwe ka thupi, chitetezo chamthupi, ndi njira zina zathupi. Mosiyana ndi zimenezi, ginsenosides ndi saponins, mtundu wa glycoside compound, ndipo amadziwika chifukwa cha adaptogenic ndi kulimbikitsa thanzi.
Ndi ginseng iti yomwe ili ndipamwamba kwambiriginsenosides?
Mitundu ya ginseng yomwe ili ndi ginsenoside yapamwamba kwambiri ndi Panax ginseng, yomwe imadziwikanso kuti Asian kapena Korea ginseng. Ginseng wamtunduwu amadziwika chifukwa cha kuchuluka kwake kwa ma ginsenosides, omwe ndi mankhwala ophatikizika omwe amachititsa kuti mbewuyo ikhale ndi thanzi labwino. Panax ginseng ndiwofunika kwambiri pamankhwala azikhalidwe ndipo nthawi zambiri amagwiritsidwa ntchito pazomwe angathe kusinthira komanso kutsitsimutsa. Mukafuna mankhwala a ginseng okhala ndi ginsenoside wambiri, Panax ginseng ndi chisankho chodziwika bwino.
Kodi ndibwino kumwa ginseng tsiku lililonse?
Nthawi zambiri zimawonedwa ngati zotetezeka kwa anthu ambiri kumwa ginseng tsiku lililonse kwa nthawi yochepa. Komabe, kugwiritsa ntchito ginseng kwanthawi yayitali tsiku lililonse kungayambitse zotsatira zoyipa kapena kuyanjana ndi mankhwala. Chifukwa chake, ndikofunikira kugwiritsa ntchito ginseng motsogozedwa ndi akatswiri azachipatala, makamaka ngati mukukonzekera kumwa tsiku lililonse kwa nthawi yayitali. Kufunsana ndi wothandizira zaumoyo kungathandize kuonetsetsa kuti ginseng ndi yoyenera pa thanzi lanu komanso kuti sagwirizana ndi mankhwala aliwonse kapena zinthu zomwe zinalipo kale.
Kodi ginseng imawonjezera testosterone?
Ginseng adanenedwa kuti ali ndi zotsatira zomwe zingatheke pamagulu a testosterone, ngakhale umboni suli wotsimikiza. Kafukufuku wina wasonyeza kuti ginseng ikhoza kukhala ndi zotsatira zochepa pa milingo ya testosterone, mwina pothandizira njira zomwe zimakhudzidwa ndi kupanga testosterone. Komabe, kafukufuku wochulukirapo akufunika kuti amvetsetse kukula kwa mphamvu ya ginseng pa testosterone.
Kodi ginseng imachita chiyani ndi mahomoni achikazi?
Ginseng ikhoza kukhala ndi zotsatira zomwe zingatheke pa mahomoni achikazi, ngakhale kuti kafukufuku m'derali sali otsimikiza. Kafukufuku wina wasonyeza kuti ginseng ikhoza kukhala ndi ma adaptogenic omwe angathandize kuti mahomoni azikhala bwino mwa amayi, makamaka panthawi yamavuto kapena kusinthasintha kwa mahomoni. Kuonjezera apo, ginseng yafufuzidwa chifukwa cha ubwino wake pothana ndi zizindikiro zokhudzana ndi kusintha kwa thupi, monga kutentha kwa thupi ndi kusintha kwa maganizo.
Nthawi yotumiza: Sep-12-2024
